When it comes to choosing which strain you’re going to use — and given how little we know about different therapeutic effects — you should mainly be choosing based on strength. Do you want to have a really strong magic mushroom experience; will you be macrodosing or microdosing; would you prefer something a little more gentle?
If there’s one thing that really separates different strains of magic mushrooms, it’s strength. Some psilocybin mushrooms are known for for being more potent than others. You might consider using a stronger strain of magic mushrooms if you’ll be macrodosing. You might also choose a stronger strain so that you have to eat less and therefore avoid any subsequent nausea.
There is some anecdotal evidence that the trips produced by certain strains are different. For example, one user on Shroomery reported having a “unique spiritual experience” using African Transekei magic mushrooms. In another thread, users report that B+ magic mushrooms have a stronger body load and a lesser visual effect.
What you’ll often hear from magic mushroom users is that “a cube is a cube”. This basically means that if it’s a magic mushroom of the species Psilocybe cubensis (most magic mushrooms available in dispensaries are cubensis species), then its effects are more or less the same.HOW TO CHOOSE A STRAIN OF MAGIC MUSHROOMS.
With that in mind, and what we mentioned about the subjective experience being a driver of the long-term effects, then choosing a strain shouldn’t be that hard. Macrodosing and microdosing can both be done with strong and weaker strains, but you might want to consider weaker mushrooms for microdosing to avoid accidental overdoses.
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We recommend the following magic mushroom strains for more gentle journeys:
HOW TO CHOOSE A STRAIN OF MAGIC MUSHROOMS.